Immunodeficiency and autoimmune disease
In this article we will provide you the information about Immunodeficiency and autoimmune disease Differences Similarities and FAQs.
What does immunodeficiency mean?
Immunodeficiency is a disorder in which the body’s immune system does not function properly, making a person more vulnerable to infectious diseases and other health conditions. This happens when the white blood cells (lymphocytes) are depleted or lack the quality of life. These patients are limited in their ability to fight bacteria, viruses, or other pathogenic organisms. Immunodeficiency can be caused by various reasons such as congenital genetic defects, prescription medication to treat certain chronic diseases , or excessive radiation to the human body. Symptoms include recurrent severe infections, skin lesions, and frequent fever. There are several different types of immunodeficiencies, from those presented from birth to those acquired during adulthood; many can be treated with appropriate biologic replacement therapy.
What does autoimmune disease mean?
An autoimmune disease is a condition in which the body’s immune system, designed to protect it from germs and other foreign substances, begins to attack the body itself. This happens when the body’s defenses confuse healthy tissues with external threats, damaging themselves. Autoimmune diseases can cause a variety of different symptoms depending on age and the area of the body affected. Some examples include juvenile rheumatoid arthritis (JRA), systemic lupus erythematosus (SLE), myasthenia gravis, celiac disease, and multiple sclerosis. Early treatment can help control symptoms related to an autoimmune disease , thus maintaining a healthy lifestyle.
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Similarities Between Immonodeficiency and Autoimmune Disease
Immunodeficiency and autoimmune diseases share basic components in their clinical presentation . Both disorders cause abnormal immune responses, resulting in a weak immune system (the former) or an overactive one (the latter). In both cases, the body cannot adequately defend itself against harmful microorganisms, increasing the risk of recurrent infections for the affected person. Furthermore, both immunodeficiency and autoimmune diseases are associated with other serious chronic problems related to the immune system; such as allergies and widespread inflammation. Lastly, both conditions require early diagnosis and ongoing treatment to minimize their negative effects.
Differences between immunodeficiency and autoimmune disease
Immunodeficiency refers to a decreased quality of life. These patients are limited in their ability of the immune system to protect the body from infection, disease, and/or cancer. This may be due to genetic factors or acquired throughout life. By contrast, autoimmune disease is when the body’s immune system mistakenly attacks its own healthy cells, causing irreversible damage. Autoimmune disorders include diseases such as systemic lupus erythematosus, rheumatoid arthritis, and primary hypothyroidism. Both conditions are serious; however, they differ mainly in that one involves too much immune system activity while the other means a low level of immune response.
Frequent questions
What does it mean to have immunodeficiency?
Immunodeficiency means that a person’s immune system is weakened or malfunctioning, making it harder for their body to fight infection and disease. People with immunodeficiency are more likely to get serious and even fatal infections, such as tuberculosis and salmonellosis.
What are immunodeficiency diseases?
Immunodeficiency diseases include acquired immunodeficiency syndrome (AIDS), primary lymphoproliferative syndrome, chronic granulomatous diseases, congenital complement disorders, and IgA deficiency. Other related conditions include Congenital Aplastic Anemia, Sezary Disease, and Primary Complement Deficiencies.
How is immunodeficiency detected?
The best way to detect an immunodeficiency is through laboratory tests to measure the levels of immune cells, such as lymphocytes and monocytes. These tests may also include measurements of the number and activity of other immune cells, such as neutrophils. Doctors also perform tests to evaluate the immune system as a whole, such as genetic tests or studies on the response to vaccines. Additionally, other physical exams may be Chinese . In addition, it was used to look for clinical signs associated with autoimmune diseases or other conditions related to the immune system.
What are the main autoimmune diseases?
Major autoimmune diseases include systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, type 1 diabetes, Hashimoto’s thyroiditis, and Crohn’s disease.
What is an autoimmune disease and why does it occur?
An autoimmune disease is a medical condition in which the body’s immune system attacks healthy tissues or produces antibodies against them. This is due to a failure of the immune system to distinguish between self and foreign; as a result, the immune system mistakes normal cells for pathogenic invaders and overreacts inappropriately. In some autoimmune diseases, the antibodies can destroy healthy cells directly, while in other cases, the inflammatory response triggered by the presence of these antibodies indirectly damages normal tissue.
